SNS Urolithin-B XT
Lean Muscle, Strength, & Improved Recovery
150 mg. Urolithin-B Per Capsule
Urolithin-B is a unique ingredient that has been shown to have both potential anabolic and anti-catabolic properties and can be used to help support increase in lean muscle & strength and optimal muscle recovery.
Urolithin-B XT Highlights/Supports:
Lean Muscle & Strength
Optimal Muscle Recovery
Muscle Protective Benefits
Anabolic & Anti-Catabolic Properties
Decreased Muscle Protein Breakdown
Increased Muscle Protein Synthesis (MPS)
Potential Anti-Estrogenic/Anti-Aromatase Properties
What is Urolithin-B?
Urolithin B is one of the four metabolites of the Ellagic Acid/Ellagitannins family. It is a type of phenolic compound that is produced in the human gut after absorption of ellagitannin containing foods such as pomegranate, strawberries, red raspberries, walnuts, and/or oak-aged red wine.
Muscle Protective Benefits:
Since Urolithin B supports muscle growth thru increased protein synthesis and decreased protein breakdown, it is theorized that it may also have a muscular protective effect during times of stress and help reduce muscular atrophy (wasting).
This could be potentially beneficial to helping preserve lean muscle tissue as we get older and also helping to preserve lean muscle while dieting.
Muscle Protein Synthesis:
The amount of muscle tissue in the human body is regulated in part by the body balancing the rates of muscle synthesis and muscle protein breakdown.
Urolithin B stimulates muscle protein synthesis via mediation of the androgen receptor (AR) pathway.
Animal studies have shown that even low doses of Urolithin B increased the diameter of myotubes.
Research has shown that Urolithin B promotes the development of muscle cells by supporting the increase in protein synthesis and inhibiting the ubiquitin-proteasome pathway
Interestingly, in one rodent study, Urolithin B was shown to support muscle growth and also decrease muscle atrophy (breakdown) in the same subjects.
Reduces/Decreases Muscle Protein Breakdown:
Urolithin B reduces muscle protein breakdown through supporting the inhibition of the ubiquitin-proteasome pathway (UPP), which is a key factor in muscle protein breakdown.
The ubiquitin-proteasome pathway is one of three key pathways of muscle protein breakdown. These pathways are:
Ubiquitin-proteasome pathway (UPP)
Calpain pathway (calpain Ca2+-dependent cysteine proteases)
Autophagy
Muscle protein breakdown is a catabolic state in which muscle cells are broken down into their individual components, providing a source of energy. Basically, any up regulation of the protein breakdown pathways will result in the reduction of muscle mass.
Research has supported that there may be a lower activity of the ubiquitin-proteasome system in myotubes exposed to Urolithin B. These results support that the faster growth of myotubes exposed to Urolithin B is due to a higher protein synthesis as well as reduced activity of the ubiquitin-proteasome system (A major protein breakdown pathway), meaning reduced protein breakdown.
The human body is generally in a constant state of protein turnover and constantly trying to balance between protein synthesis and protein breakdown. A higher synthesis rate as well as a lower breakdown rate will increase the net protein balance of the muscles, increasing growth.
Anti-Aromatase & Anti-Estrogenic Activity Support Potential:
Urolithin B, like other members of the urolithin family, has been shown to support the inhibition of the aromatase enzyme; a key enzyme that helps prevent testosterone from being converted to estrogen.
Note: Manufacturers continually change product specifications. While we try our best to keep product descriptions up to date, they do not necessarily reflect the latest information available from the manufacturer. We are not responsible for incorrect or outdated product descriptions and/or images.
